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Patient-reported impacts of a conservative management programme for the clinically inapparent adrenal mass.
[adrenal incidentaloma]
The
aim
of
this
study
was
to
assess
patient-reported
impacts
and
health-related
quality
of
life
(
HRQL
)
of
a
2
-
year
follow-up
programme
in
a
large
cohort
of
patients
with
stationary
,
non-functioning
,
adrenal
incidentalomas
(
AIs
)
in
western
Sweden
.
145
patients
(
mean
age
68
years
,
62
%
females
)
with
AI
from
a
prospective
study
in
western
Sweden
were
studied
.
All
had
completed
a
2
-
year
follow-up
programme
by
November
2007
,
without
evidence
of
adrenal
malignancy
or
hormone
over-production
.
To
evaluate
patient-reported
impacts
and
HRQL
,
an
eight
-item
adrenal
incidentaloma
impact
questionnaire
was
used
retrospectively
,
together
with
the
hospital
anxiety
and
depression
scale
,
and
the
short
form-
36
.
There
were
111
patients
(
mean
age
67
years
,
63
%
females
)
who
responded
to
the
questionnaire
(
response
rate
77
%
)
.
77
%
reported
that
the
AI
diagnosis
had
caused
them
to
be
worried
;
however
,
fewer
than
20
%
had
thought
about
the
lesion
often
during
the
follow-up
programme
,
and
only
3
%
had
felt
that
it
had
a
large
impact
on
their
current
daily
life
.
Only
4
%
stated
that
the
follow-up
programme
had
been
a
negative
experience
,
nevertheless
10
%
reported
a
negative
impact
on
their
HRQL
during
the
follow-up
programme
.
Only
2
%
stated
that
release
from
follow-up
caused
worry
to
any
degree
.
In
total
,
29
%
had
possible
anxiety
,
and
30
%
had
possible
depression
,
probably
reflecting
significant
co
-morbidity
.
Possible
anxiety
correlated
with
a
more
negative
experience
of
the
follow-up
programme
.
In
conclusion
,
the
2
-
year
follow-up
programme
for
patients
with
AI
was
well
tolerated
.
Nonetheless
,
a
small
number
remained
worried
throughout
follow-up
,
suggesting
the
need
for
tailored
counselling
in
individual
patients
to
ameliorate
negative
impacts
of
follow-up
.
Diseases
Validation
Diseases presenting
"probably reflecting significant co-morbidity"
symptom
adrenal incidentaloma
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