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Minimally Invasive Esophagectomy for Dysplastic Barrett's Esophagus.
[esophageal adenocarcinoma]
A
substantial
portion
of
patients
diagnosed
preoperatively
with
high
grade
dysplasia
(
HGD
)
alone
will
have
occult
esophageal
adenocarcinoma
on
analysis
of
the
surgical
specimen
.
Therefore
,
because
of
an
increased
risk
of
disease
progression
and
malignancy
,
patients
with
HGD
should
be
referred
for
esophagectomy
promptly
when
endoscopic
therapy
has
failed
.
The
required
extent
of
lymphadenectomy
in
this
cohort
of
patients
is
unknown
because
of
the
variable
incidence
of
submucosal
cancer
observed
.
Improvements
in
perioperative
care
,
adoption
of
a
minimally
invasive
surgical
approach
,
and
centralization
of
esophageal
cancer
services
have
substantially
reduced
the
rates
of
mortality
and
morbidity
associated
with
esophagectomy
in
recent
years
.
Minimally
invasive
esophagectomy
should
be
considered
the
treatment
of
choice
in
patients
with
dysplastic
Barrett
's
esophagus
that
is
refractory
to
endoscopic
therapy
or
those
at
high
risk
of
invasive
cancer
.
Diseases
Validation
Diseases presenting
"high risk"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
adrenal incidentaloma
alpha-thalassemia
aniridia
canavan disease
congenital diaphragmatic hernia
congenital toxoplasmosis
cowden syndrome
cushing syndrome
cutaneous mastocytosis
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
fabry disease
harlequin ichthyosis
heparin-induced thrombocytopenia
hirschsprung disease
hodgkin lymphoma, classical
homocystinuria without methylmalonic aciduria
hydrocephalus with stenosis of the aqueduct of sylvius
krabbe disease
legionellosis
liposarcoma
locked-in syndrome
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
pendred syndrome
phenylketonuria
primary hyperoxaluria type 1
severe combined immunodeficiency
sneddon syndrome
waldenström macroglobulinemia
werner syndrome
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