Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Esophageal Adenocarcinoma and Its Rare Association with Barrett's Esophagus in Henan, China.
[esophageal adenocarcinoma]
Incidence
of
esophageal
adenocarcinoma
(
EAC
)
has
increased
sharply
in
Western
Europe
and
United
States
over
the
past
three
decades
.
Nearly
all
cases
of
EAC
in
the
west
are
thought
to
be
associated
with
Barrett
's
esophagus
(
BE
)
at
the
time
of
diagnosis
.
Regions
in
the
Henan
province
of
China
have
one
of
world
's
highest
incidences
of
esophageal
cancer
,
yet
recent
temporal
trends
in
the
relative
rates
of
EAC
with
respect
to
esophageal
squamous-cell
carcinoma
(
ESCC
)
,
as
well
as
its
association
with
Barrett
's
esophagus
(
BE
)
,
have
not
been
reported
.
In
this
report
,
we
present
large
-scale
longitudinal
clinical
and
histological
data
on
5401
esophageal
cancers
(
EC
)
patients
diagnosed
during
the
recent
10
-
year
period
(
2002
-
2011
)
at
Henan
Cancer
Hospital
,
China
.
All
217
esophageal
adenocarcinoma
(
EAC
)
patients
from
these
5401
EC
patients
were
examined
to
better
understand
the
relationship
between
Barrett
's
esophagus
(
BE
)
and
EAC
.
We
found
that
EAC
was
relatively
rare
and
accounted
for
approximately
5
%
of
all
esophageal
cancers
each
year
during
2002
-
2011
.
There
is
no
evidence
of
significant
temporal
trends
in
the
rate
of
EAC
relative
to
ESCC
.
Only
10
out
of
217
(
4
.
6
%
)
EAC
cases
were
detected
to
have
any
evidence
of
Barrett
's
esophagus
.
This
result
raises
the
possibility
of
a
different
etiological
basis
for
EAC
in
China
motivating
more
detailed
epidemiological
,
clinical
and
molecular
characterization
of
EAC
in
China
in
order
to
better
understand
the
neoplastic
development
of
EAC
.
