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Management of Barrett's esophagus and early esophageal cancer: update on endoscopic treatment strategies.
[esophageal adenocarcinoma]
Barrett
's
esophagus
represents
the
strongest
known
risk
factor
for
developing
esophageal
adenocarcinoma
.
The
traditional
management
strategy
for
identifying
and
managing
Barrett
's
esophagus
involves
screening
and
endoscopic
surveillance
to
identify
early
stage
,
curable
carcinoma
.
Recently
,
endoscopic
eradication
therapy
has
emerged
to
achieve
the
complete
eradication
of
Barrett
's
esophagus
and
intramucosal
cancer
to
prevent
the
development
of
invasive
cancer
with
lymphatic
spread
.
Randomized
trials
have
demonstrated
the
efficacy
of
these
approaches
to
reduce
the
progression
to
cancer
,
and
endoscopic
eradication
therapy
has
become
the
preferred
treatment
approach
for
patients
with
high
--grade
dysplasia
,
and
may
be
utilized
for
management
of
low
--grade
dysplasia
as
well
.
Owing
to
excellent
eradication
rates
and
favorable
side
effect
profile
,
radio
frequency
ablation
has
emerged
as
the
ablative
strategy
of
choice
for
patients
undergoing
endoscopic
eradication
therapy
.
Diseases
Validation
Diseases presenting
"early stage"
symptom
adrenomyeloneuropathy
allergic bronchopulmonary aspergillosis
aromatase deficiency
cadasil
carcinoma of the gallbladder
child syndrome
cholangiocarcinoma
congenital adrenal hyperplasia
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
harlequin ichthyosis
hereditary cerebral hemorrhage with amyloidosis
hodgkin lymphoma, classical
kindler syndrome
lymphangioleiomyomatosis
neonatal adrenoleukodystrophy
pyomyositis
scrub typhus
sneddon syndrome
typhoid
von hippel-lindau disease
zellweger syndrome
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