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Management of Barrett's esophagus and early esophageal cancer: update on endoscopic treatment strategies.
[esophageal adenocarcinoma]
Barrett
's
esophagus
represents
the
strongest
known
risk
factor
for
developing
esophageal
adenocarcinoma
.
The
traditional
management
strategy
for
identifying
and
managing
Barrett
's
esophagus
involves
screening
and
endoscopic
surveillance
to
identify
early
stage
,
curable
carcinoma
.
Recently
,
endoscopic
eradication
therapy
has
emerged
to
achieve
the
complete
eradication
of
Barrett
's
esophagus
and
intramucosal
cancer
to
prevent
the
development
of
invasive
cancer
with
lymphatic
spread
.
Randomized
trials
have
demonstrated
the
efficacy
of
these
approaches
to
reduce
the
progression
to
cancer
,
and
endoscopic
eradication
therapy
has
become
the
preferred
treatment
approach
for
patients
with
high
--grade
dysplasia
,
and
may
be
utilized
for
management
of
low
--grade
dysplasia
as
well
.
Owing
to
excellent
eradication
rates
and
favorable
side
effect
profile
,
radio
frequency
ablation
has
emerged
as
the
ablative
strategy
of
choice
for
patients
undergoing
endoscopic
eradication
therapy
.
Diseases
Validation
Diseases presenting
"intramucosal cancer to prevent the development of invasive cancer with lymphatic spread"
symptom
esophageal adenocarcinoma
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