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A random Abstract
Our Project
Our Team
Biomarkers of Barrett's esophagus.
[esophageal adenocarcinoma]
Barrett
's
esophagus
is
the
strongest
risk
for
esophageal
adenocarcinoma
(
EAC
)
.
Metaplasia
in
patients
with
BE
may
progress
to
dysplasia
and
then
invasive
carcinoma
.
Well-defined
diagnostic
,
progressive
,
predictive
,
and
prognostic
biomarkers
are
needed
to
identify
the
presence
of
the
disease
,
estimate
the
risk
of
malignant
transformation
,
and
predict
the
therapeutic
outcome
and
survival
of
EAC
patients
.
There
are
many
predictive
and
prognostic
markers
that
lack
substantial
validation
,
and
do
not
allow
stratification
of
patients
with
gastroesophageal
reflux
disease
in
clinical
practice
for
outcome
and
effectiveness
of
therapy
.
In
this
short
review
we
summarize
the
current
knowledge
regarding
possible
biomarkers
,
focusing
on
the
pathophysiologic
mechanisms
to
improve
prognostic
and
therapeutic
approaches
.
Diseases
Validation
Diseases presenting
"then invasive carcinoma"
symptom
esophageal adenocarcinoma
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