Phototolerance induced by narrow-band UVB phototherapy in severe erythropoietic protoporphyria.

[erythropoietic protoporphyria]

Erythropoietic protoporphyria arises from an inherited disorder of porphyrin metabolism which leads to an accumulation of protoporphyrin IX in the erythropoietic system and other tissues . It is characterized by cutaneous photosensitivity , usually difficult to keep under control . Among the scant therapeutic options proposed to reduce photosensitivity in erythropoietic protoporphyria , narrow -band UVB phototherapy has occasionally been used to induce sunlight tolerance . We report an adult case of erythropoietic protoporphyria with a severe photosensitivity treated with narrow -band UVB that developed an appropriate sunlight phototolerance , without adverse events during phototherapy .