X-linked dominant protoporphyria: a new porphyria.

[erythropoietic protoporphyria]

X-linked dominant protoporphyria (XLDPP ) was first reported in the genetics literature in 2008 . It has a phenotype very similar to erythropoietic protoporphyria (EPP ), but is distinguished from EPP by higher concentrations of erythrocyte protoporphyrin (of which a high proportion is zinc-chelated ), its apparently higher incidence of liver disease , and an X-linked dominant pattern of inheritance . Dermatologists should understand how XLDPP differs from EPP , in order to advise newly diagnosed patients correctly about the genetic implications and the long -term management strategy . We present a case series of XLDPP to introduce this condition to the dermatology literature .