Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Xanthomatous hypophysitis.
[erdheim-chester disease]
Xanthomatous
hypophysitis
(
XH
)
is
the
rarely
seen
primary
form
of
hypophysitis
.
The
histological
differential
diagnosis
includes
other
causes
of
hypophysitis
,
Erdheim-
Chester
disease
(
ECD
)
,
Langerhans
cell
histiocytosis
,
Rosai-
Dorfman
disease
and
plasma
cell
granulomas
.
We
present
a
39
-
year
-old
woman
admitted
to
our
department
with
headache
,
menstrual
irregularity
and
galactorrhea
.
The
MRI
revealed
a
lesion
with
a
central
cystic
/
necrotic
region
and
a
diameter
of
almost
1
cm
.
Histologic
examination
showed
an
inflammatory
infiltrate
of
numerous
foamy
histiocytes
,
surrounding
the
necrotic
tissue
.
On
immunohistochemical
sections
,
infiltrating
foamy
cells
stained
strongly
positive
for
CD
68
,
and
negative
for
CD
1
a
and
S
100
.
After
establishing
the
diagnosis
of
XH
,
the
patient
underwent
glucocorticoid
treatment
.
XH
should
be
considered
in
the
differential
diagnosis
of
pituitary
lesions
.
Since
XH
is
rare
,
it
is
difficult
to
assess
the
efficacy
of
medical
/
surgical
treatment
of
this
entity
accurately
.
