Erdheim-Chester disease detected with 99mTc MDP bone SPECT/CT.

[erdheim-chester disease]

Erdheim-Chester disease (ECD ) is a rare non-Langerhans ' cell histiocytosis . Mild but permanent juxta-articular bone pain in mainly knees and ankles is the most frequent associated symptom . Despite the pathognomonic radiographic findings , most cases are still diagnosed by the pathologist .The lesions consist of lipid-storing CD 68 +/CD 1 a--non-Langerhans ' cell histiocytes , most frequently localized in bone but also involving multiple organ systems in the body . We present a case report in which the diagnosis of ECD was established with 99 mTc MDP bone SPECT /CT .

Diseases
Validation

Diseases presenting "histiocytosis" symptom

child syndrome

cutaneous mastocytosis

dentin dysplasia

dentinogenesis imperfecta

erdheim-chester disease

kallmann syndrome

lymphangioleiomyomatosis

omenn syndrome

papillon-lefèvre syndrome

This symptom has already been validated