Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Visceral fat accumulation and postdexamethasone serum cortisol levels in patients with adrenal incidentaloma.
[adrenal incidentaloma]
Visceral
fat
is
a
significant
cardiovascular
risk
factor
.
Because
visceral
fat
has
not
been
measured
systematically
in
patients
with
adrenal
incidentalomas
,
we
have
tested
the
hypothesis
that
visceral
fat
volume
may
be
associated
with
cutoffs
for
serum
cortisol
levels
post
dexamethasone
.
This
was
a
retrospective
,
cross-sectional
study
.
The
study
was
conducted
at
the
Endocrine
Investigation
Unit
,
University
Teaching
Hospital
.
Seventy
-
three
women
and
52
men
diagnosed
with
adrenal
incidentalomas
and
9
patients
with
overt
Cushing
's
syndrome
participated
in
this
study
.
The
following
was
measured
for
serum
cortisol
level
after
dexamethasone
suppression
and
visceral
fat
ratios
:
visceral-
subcutaneous
(
V
:
S
)
and
visceral-
total
volume
(
V
:
TV
)
measured
by
computed
tomography
.
Sixty
-
eight
patients
with
a
postdexamethasone
serum
cortisol
greater
than
1
.
8
μg
/
dL
(
50
nmol
/
L
)
showed
a
significantly
higher
mean
V
:
S
and
V
:
TV
fat
ratio
compared
with
those
whose
serum
cortisol
was
less
than
1
.
8
μg
/
dL
:
women
,
lnV
:
S
,
-
0
.
45
vs
-
0
.
69
[
mean
difference
0
.
24
(
95
%
confidence
interval
[
CI
]
0
.
08
-
0
.
41
)
;
P
=
.
004
]
and
V
:
TV
,
0
.
39
vs
0
.
34
[
mean
difference
0
.
05
(
95
%
CI
0
.
02
-
0
.
09
)
;
P
=
.
004
]
;
men
,
lnV
:
S
,
0
.
64
vs
0
.
29
[
mean
difference
0
.
35
95
%
CI
0
.
08
-
0
.
63
)
;
P
=
.
01
]
and
V
:
TV
,
0
.
65
vs
0
.
57
[
mean
difference
0
.
08
(
95
%
CI
0
.
02
-
0
.
14
)
;
P
=
.
02
]
.
By
ANOVA
and
post
hoc
analysis
(
Fisher
's
least
significant
differences
)
,
there
was
no
difference
in
fat
ratios
between
the
postdexamethasone
serum
cortisol
groups
[
1
.
8
-
2
.
9
μg
/
dL
(
50
-
82
nmol
/
L
)
,
3
.
0
-
5
.
0
μg
/
dL
(
83
-
137
nmol
/
L
)
,
>
5
.
0
μg
/
dL
(
>
138
nmol
/
L
)
and
Cushing
's
syndrome
(
mean
V
:
TV
:
0
.
38
,
0
.
40
,
0
.
40
,
0
.
41
,
respectively
)
]
,
but
they
all
differed
significantly
from
the
less
than
the
1
.
8
-
μg
/
dL
group
(
V
:
TV
:
0
.
34
,
P
=
.
03
)
.
Visceral
fat
is
increased
in
patients
with
adrenal
incidentalomas
and
a
postdexamethasone
serum
cortisol
of
greater
than
1
.
8
μg
/
dL
and
is
similar
to
that
found
in
patients
with
overt
Cushing
's
syndrome
.
Diseases
Validation
Diseases presenting
"we have tested the hypothesis that visceral fat volume may be associated with cutoffs for serum cortisol levels post dexamethasone"
symptom
adrenal incidentaloma
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom