Rare Diseases Symptoms Automatic Extraction

Epidermolysis bullosa pruriginosa showing good response to low-dose thalidomide - a report of two cases.

[dystrophic epidermolysis bullosa]

Epidermolysis bullosa pruriginosa is a rare distinctive variant of dystrophic epidermolysis bullosa characterized by intense pruritus, lichenified plaques in linear distribution, and anonychia. It is a difficult condition to treat and causes a great deal of distress. The present authors report two cases showing good response to low-dose thalidomide, with clinical and symptomatic improvement. The exact mechanism of action is not yet clear.

Diseases presenting "pruritus" symptom

  • benign recurrent intrahepatic cholestasis
  • cholangiocarcinoma
  • cutaneous mastocytosis
  • dystrophic epidermolysis bullosa
  • erdheim-chester disease
  • lamellar ichthyosis
  • pleomorphic liposarcoma
  • pyomyositis
  • zellweger syndrome

This symptom has already been validated