Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Advances in understanding and treating dystrophic epidermolysis bullosa.
[dystrophic epidermolysis bullosa]
Epidermolysis
bullosa
is
a
group
of
inherited
disorders
that
can
be
both
systemic
and
life-threatening
.
Standard
treatments
for
the
most
severe
forms
of
this
disorder
,
typically
limited
to
palliative
care
,
are
ineffective
in
reducing
the
morbidity
and
mortality
due
to
complications
of
the
disease
.
Emerging
therapies-such
as
the
use
of
allogeneic
cellular
therapy
,
gene
therapy
,
and
protein
therapy-have
all
shown
promise
,
but
it
is
likely
that
several
approaches
will
need
to
be
combined
to
realize
a
cure
.
For
recessive
dystrophic
epidermolysis
bullosa
,
each
particular
therapeutic
approach
has
added
to
our
understanding
of
type
VII
collagen
(
C
7
)
function
and
the
basic
biology
surrounding
the
disease
.
The
efficacy
of
these
therapies
and
the
mechanisms
by
which
they
function
also
give
us
insight
into
developing
future
strategies
for
treating
this
and
other
extracellular
matrix
disorders
.
