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Non-functioning adrenal incidentalomas are associated with higher hypertension prevalence and higher risk of atherosclerosis.
[adrenal incidentaloma]
Adrenal
incidentalomas
(
AIs
)
have
been
associated
with
an
increased
incidence
of
several
cardiovascular
risk
factors
.
The
aim
of
this
study
was
to
investigate
plasma
adiponectin
,
leptin
,
resistin
,
homocysteine
,
high
sensitive
C-
reactive
protein
levels
,
and
carotid
intima
media
thickness
(
CIMT
)
in
patients
with
non-functioning
AI
(
NFAI
)
.
This
study
included
data
from
28
patients
with
NFAI
(
Group
1
)
and
41
controls
(
Group
2
)
.
Of
the
patients
,
50
were
female
and
19
were
male
,
and
the
mean
age
was
46
.
7
(
range
37
-
65
)
years
.
There
were
no
significant
differences
between
Group
1
and
2
in
terms
of
age
,
sex
,
or
BMI
.
Hypertension
prevalence
was
significantly
higher
in
the
NFAI
group
than
in
the
control
group
(
p
Â
=
Â
0
.
01
)
.
Both
groups
had
similar
lipid
,
blood
glucose
,
homocysteine
,
uric
acid
,
high
-sensitivity
CRP
levels
.
Adiponectin
,
leptin
,
and
resistin
levels
were
similar
in
both
groups
.
CIMTs
were
significantly
higher
in
the
NFAI
group
.
There
is
increasing
evidence
that
several
cardiometabolic
risk
factors
occur
with
higher
prevalence
in
non-functioning
adrenal
incidentaloma
patients
compared
to
age-matched
healthy
subjects
.
In
our
study
,
hypertension
prevalence
and
CIMT
were
higher
in
the
NFAI
group
.
Serum
adipokine
levels
were
similar
for
both
groups
.
Diseases
Validation
Diseases presenting
"increased incidence of several cardiovascular risk factors"
symptom
adrenal incidentaloma
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