Non-functioning adrenal incidentalomas are associated with higher hypertension prevalence and higher risk of atherosclerosis.

[adrenal incidentaloma]

Adrenal incidentalomas (AIs ) have been associated with an increased incidence of several cardiovascular risk factors . The aim of this study was to investigate plasma adiponectin , leptin , resistin , homocysteine , high sensitive C-reactive protein levels , and carotid intima media thickness (CIMT ) in patients with non-functioning AI (NFAI ).This study included data from 28 patients with NFAI (Group 1 ) and 41 controls (Group 2 ). Of the patients , 50 were female and 19 were male , and the mean age was 46 .7 (range 37 -65 ) years .There were no significant differences between Group 1 and 2 in terms of age , sex , or BMI . Hypertension prevalence was significantly higher in the NFAI group than in the control group (p Â =Â 0 .01 ). Both groups had similar lipid , blood glucose , homocysteine , uric acid , high -sensitivity CRP levels . Adiponectin , leptin , and resistin levels were similar in both groups . CIMTs were significantly higher in the NFAI group .There is increasing evidence that several cardiometabolic risk factors occur with higher prevalence in non-functioning adrenal incidentaloma patients compared to age-matched healthy subjects . In our study , hypertension prevalence and CIMT were higher in the NFAI group . Serum adipokine levels were similar for both groups .

Diseases
Validation

Diseases presenting "carotid intima media thickness" symptom

acute rheumatic fever

adrenal incidentaloma

congenital adrenal hyperplasia

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