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Rhythm and conduction analysis of patients with acute rheumatic fever.
[acute rheumatic fever]
Various
rhythm
and
conduction
abnormalities
can
develop
in
acute
rheumatic
fever
.
This
study
investigated
rhythm
and
conduction
abnormalities
in
children
with
acute
rheumatic
fever
using
a
standard
12
-
lead
electrocardiogram
and
24
-
h
rhythm
Holter
recordings
.
This
multicenter
retrospective
study
,
performed
between
August
2011
and
March
2012
,
enrolled
73
consecutive
children
with
acute
rheumatic
fever
.
Standard
electrocardiography
was
used
to
measure
PR
and
corrected
QT
intervals
.
Holter
recordings
were
evaluated
for
all
the
patients
,
and
52
of
the
patients
(
71
.
2
%
)
had
carditis
that
was
either
isolated
or
together
with
other
major
criteria
.
A
positive
correlation
was
detected
between
carditis
and
the
mean
PR
interval
on
standard
electrocardiography
,
but
this
was
not
significant
(
p
>
0
.
05
)
.
Standard
electrocardiography
showed
a
significant
positive
correlation
between
PR
and
corrected
QT
intervals
(
p
=
0
.
03
;
r
=
0
.
55
)
.
Standard
electrocardiography
showed
only
three
patients
(
4
.
2
%
)
with
premature
contractions
,
whereas
24
-
h
electrocardiography
showed
26
patients
(
35
.
6
%
)
with
premature
contractions
.
Carditis
was
positively
correlated
with
premature
contractions
(
p
<
0
.
01
;
r
=
0
.
57
)
.
One
patient
with
junctional
rhythm
and
one
patient
with
left
bundle
block
were
detected
by
standard
electrocardiography
.
Whereas
some
patients
with
carditis
exhibited
no
arrhythmic
evidence
on
standard
electrocardiograms
,
complete
atrioventricular
block
,
supraventricular
tachycardia
,
and
Mobitz
type
1
block
were
observed
on
24
-
h
Holter
recordings
.
A
positive
correlation
also
was
observed
between
the
presence
of
premature
contractions
and
serum
levels
of
acute
-phase
reactants
(
p
=
0
.
03
;
r
=
0
.
62
)
.
These
findings
led
to
the
conclusion
that
rhythm
and
conduction
disorders
in
acute
rheumatic
fever
are
more
common
than
previously
thought
.
Diseases
Validation
Diseases presenting
"complete atrioventricular block"
symptom
acute rheumatic fever
holt-oram syndrome
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