Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Assessment of dysplastic dentin in osteogenesis imperfecta and dentinogenesis imperfecta.
[dentin dysplasia]
Two
semiquantitative
scoring
systems
,
Clinical
Radiographic
Score
(
CRS
)
and
Dysplastic
Dentin
Score
(
DDS
)
,
were
introduced
for
analyzing
degree
of
dysplastic
manifestations
in
dentin
.
The
utility
of
both
systems
was
demonstrated
in
a
large
material
of
teeth
from
patients
with
dentinogenesis
imperfecta
(
DI
)
and
osteogenesis
imperfecta
(
OI
)
.
Twenty
teeth
from
healthy
controls
,
81
teeth
from
40
patients
with
OI
,
and
18
teeth
with
DI
without
OI
(
DI
type
II
)
were
examined
.
The
degree
of
dysplasia
was
correlated
with
type
and
form
of
OI
and
type
of
DI
.
The
median
DDS
did
not
differ
between
DI
associated
with
OI
(
DI
type
I
)
and
DI
type
II
.
DDS
in
OI
patients
without
clinical
signs
of
DI
was
above
that
of
control
teeth
.
Both
circumpulpal
and
mantle
dentin
showed
increased
DDS
,
although
circumpulpal
dentin
was
more
severely
affected
.
The
median
DDS
was
highest
for
the
most
severe
type
of
non-
lethal
OI
(
type
III
)
.
DDS
increased
significantly
with
form
(
severity
)
of
OI
.
A
significant
association
between
DDS
and
CRS
was
found
,
although
diagnosis
of
DI
in
less
severe
cases
was
not
possible
based
on
radiographic
or
clinical
signs
alone
.
Thus
,
the
DDS
system
proved
valuable
when
the
CRS
system
based
on
radiographic
/
clinical
manifestations
failed
,
the
most
significant
finding
being
subclinical
histological
manifestations
of
DI
in
patients
with
OI
but
without
clinical
or
radiographic
signs
of
DI
.
These
subtle
dysplastic
changes
are
most
likely
an
expression
of
genetic
disturbances
associated
with
OI
and
should
not
be
diagnosed
as
DI
,
but
rather
be
termed
histologic
manifestations
of
dysplastic
dentin
associated
with
OI
.
