Rare Diseases Symptoms Automatic Extraction
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A national prospective surveillance study of acute rheumatic fever in Australian children.
[acute rheumatic fever]
Acute
rheumatic
fever
(
ARF
)
is
an
important
cause
of
heart
disease
in
Indigenous
people
of
northern
and
central
Australia
.
However
,
little
is
known
about
ARF
in
children
across
all
Australian
population
groups
.
This
national
prospective
study
was
conducted
to
determine
patterns
of
disease
,
and
populations
and
regions
at
highest
risk
.
The
Australian
Paediatric
Surveillance
Unit
surveillance
model
was
used
to
collect
data
on
children
with
ARF
across
Australia
.
Children
up
to
15
years
of
age
were
included
if
they
had
an
ARF
episode
diagnosed
between
October
1
,
2007
and
December
31
,
2010
that
met
the
case
definition
.
ARF
was
identified
in
151
children
:
131
Indigenous
Australians
,
10
non-
Indigenous
Australians
,
8
Pacific
Islanders
and
1
African
(
1
unknown
)
.
Common
presenting
features
were
joint
symptoms
,
fever
and
carditis
.
Sydenham
chorea
was
reported
in
19
%
of
children
.
Aseptic
monoarthritis
was
a
major
manifestation
in
19
%
of
high
-risk
children
.
Seven
non-
Indigenous
Australian
children
presented
with
classic
,
highly
specific
features
compared
with
23
%
of
high
-risk
children
,
suggesting
that
subtle
presentations
of
ARF
are
being
missed
in
non-
Indigenous
children
.
Recent
sore
throat
was
reported
in
33
%
of
cases
,
including
25
%
of
remote
Indigenous
children
.
There
were
delays
in
presentation
to
care
and
referral
to
higher-level
care
across
urban
/
rural
and
remote
areas
.
ARF
may
be
more
common
than
previously
thought
among
low
-risk
children
.
These
data
should
prompt
an
awareness
of
ARF
diagnosis
and
management
across
all
regions
,
including
strategies
for
primary
prevention
.
There
should
be
renewed
emphasis
on
treatment
of
sore
throat
in
high
-risk
groups
.
Diseases
Validation
Diseases presenting
"recent sore throat"
symptom
acute rheumatic fever
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