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[Nineteen cases of school-aged children with degenerative or metabolic neurological disorders initially presenting with learning difficulty and/or behavior disturbance].
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We reported 19 cases of school -aged children . They were initially judged to have learning difficulty or school maladaptation because of attention deficits , hyperactive behaviors or poor school performance , followed by the diagnosis such as degenerative or metabolic neurological diseases . The patients consisted of 4 cases of adrenoleukodystrophy , 5 cases of dentatorubral-pallidoluysian atrophy , 3 cases of Sanfilippo syndrome , 3 cases of subacute sclerosing panencephalitis , and each one case of juvenile Gaucher disease , juvenile Huntington disease , juvenile metachromatic leukodystrophy and Leigh disease . They had markedly poor school performance , and / or abnormal behaviors , followed by seizures , character disorders or psychomotor regression . The diagnostic clues included brain CT scan and / or MRI , peculiar facial appearance and notable family histories . When the children were indicated to have learning difficulty or maladjustment to school life , we should make deliberate differential diagnoses before concluding that they have a learning disorder and / or attention -deficit / hyperactivity disorder . Instead they should be recommended to visit child neurologists , when they present with any problems as aforesaid .
