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Cervical dedifferentiated liposarcoma with meningothelial-like whorling.
[dedifferentiated liposarcoma]
Liposarcomas
are
the
most
common
soft
-tissue
sarcoma
of
adults
,
but
rare
in
the
head
and
neck
.
Recently
,
a
subtype
of
dedifferentiated
liposarcoma
with
meningiothelial-like
whorls
was
reported
and
we
present
the
first
description
of
such
a
tumor
in
the
head
and
neck
.
A
65
Â
year
old
male
underwent
a
resection
of
a
calcified
retroesophageal
mass
that
was
in
close
relation
to
the
left
hemithyroid
and
recurrent
laryngeal
nerve
.
It
was
resected
en
bloc
with
the
left
thyroid
lobe
.
Initial
pathologic
evaluation
suggested
the
mass
was
a
schwanomma
of
the
recurrent
laryngeal
nerve
,
but
positive
staining
for
MDM
2
and
CDK
4
indicated
the
tumor
was
a
dedifferentiated
liposarcoma
.
Further
evaluation
elucidated
the
unique
meningothelial-like
whorls
within
the
tumor
.
This
case
demonstrates
dedifferentiated
liposarcomas
do
appear
in
the
head
and
neck
.
Furthermore
,
this
is
the
first
report
in
the
head
and
neck
of
the
mengiothelial-like
whorling
pattern
type
of
dedifferentiated
liposarcoma
.
