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[A case of liposarcoma of the abdominal wall complicated by thrombocytpenia as a paraneoplastic syndrome].
[dedifferentiated liposarcoma]
A
59
-
year
-old
woman
was
admitted
to
our
hospital
because
of
right
chest
pain
.
CT
scan
showed
a
mass
on
the
right
abdominal
wall
and
bilateral
pleural
effusion
.
The
histological
diagnosis
following
core
needle
biopsy
was
undifferentiated
sarcoma
.
The
right
pleural
effusion
gradually
increased
despite
negative
cytology
.
Although
we
planned
chemotherapy
for
the
clinically
diagnosed
pleural
invasion
,
thrombocytopenia
as
a
paraneoplastic
syndrome
appeared
.
The
minimum
thrombocyte
count
was
4
,
000
/
mm
3
.
While
transfusion
was
not
effective
,
per
os
dexamethasone
at
2
.
0
mg
/
day
kept
the
thrombocyte
count
at
around
6
×
10
4
/
mm
3
.
Anti-thrombocyte
antibody
was
negative
.
Tumor
resection
surgery
with
partial
diaphragm
resection
and
11
th
and
12
th
rib
resection
,
and
abdominal
wall
plasty
with
mesh
was
performed
.
The
final
histological
diagnosis
was
dedifferentiated
liposarcoma
.
The
thrombocyte
count
returned
to
the
normal
range
just
after
the
operation
.
However
,
she
died
of
pleural
dissemination
,
peritoneal
dissemination
,
and
local
recurrence
69
days
after
the
operation
.
Diseases
Validation
Diseases presenting
"abdominal wall plasty"
symptom
dedifferentiated liposarcoma
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