[A case of liposarcoma of the abdominal wall complicated by thrombocytpenia as a paraneoplastic syndrome].

[dedifferentiated liposarcoma]

A 59 -year -old woman was admitted to our hospital because of right chest pain . CT scan showed a mass on the right abdominal wall and bilateral pleural effusion . The histological diagnosis following core needle biopsy was undifferentiated sarcoma . The right pleural effusion gradually increased despite negative cytology . Although we planned chemotherapy for the clinically diagnosed pleural invasion , thrombocytopenia as a paraneoplastic syndrome appeared . The minimum thrombocyte count was 4 ,000 /mm 3 . While transfusion was not effective , per os dexamethasone at 2 .0 mg /day kept the thrombocyte count at around 6 ×10 4 /mm 3 . Anti-thrombocyte antibody was negative . Tumor resection surgery with partial diaphragm resection and 11 th and 12 th rib resection , and abdominal wall plasty with mesh was performed . The final histological diagnosis was dedifferentiated liposarcoma . The thrombocyte count returned to the normal range just after the operation . However , she died of pleural dissemination , peritoneal dissemination , and local recurrence 69 days after the operation .