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Equivalent cross-relaxation rate imaging positively correlates with pathological grade and cell density of adipocytic tumors.
[dedifferentiated liposarcoma]
Equivalent
cross-relaxation
rate
imaging
(
ECRI
)
is
an
MRI
technique
used
to
evaluate
qualitative
changes
in
protein-water
interactions
.
We
aimed
to
prospectively
evaluate
the
utility
of
ECRI
for
classification
of
adipocytic
tumors
.
I
nstitutional
Review
Board
approval
was
obtained
and
all
patients
provided
informed
consent
.
Study
participants
included
40
patients
with
adipocytic
tumors
who
were
diagnosed
with
lipomas
(
n
=
22
)
,
atypical
lipomatous
tissue
/
well-differentiated
liposarcoma
(
ALT
/
WDL
;
n
=
9
)
,
myxoid
/
round
cell
liposarcoma
(
MyL
;
n
=
6
)
,
and
dedifferentiated
liposarcoma
(
DDL
;
n
=
3
)
,
and
20
control
patients
for
whom
subcutaneous
fat
in
the
buttock
or
thigh
was
analyzed
.
Mean
ECR
values
of
lipomas
,
ALT
/
WDL
,
and
subcutaneous
fat
were
low
,
and
those
of
MyL
and
DDL
were
high
.
Mean
ECR
values
of
MyL
and
DDL
were
significantly
higher
than
those
of
ALT
/
WDL
.
The
cut-off
value
was
5
.
1
%
.
There
was
a
positive
correlation
between
ECR
value
,
pathological
grade
,
and
cell
density
in
adipocytic
tumors
.
T
he
ECR
value
positively
correlates
with
pathological
grade
and
cell
density
of
adipocytic
tumors
.
Our
findings
suggest
that
ECRI
is
a
useful
method
for
preoperative
evaluation
of
adipocytic
tumors
.
Diseases
Validation
Diseases presenting
"positive correlation"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
adrenal incidentaloma
aromatase deficiency
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cutaneous mastocytosis
dedifferentiated liposarcoma
familial mediterranean fever
hodgkin lymphoma, classical
inclusion body myositis
kallmann syndrome
legionellosis
oral submucous fibrosis
trochlear dysplasia
well-differentiated liposarcoma
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