Rare Diseases Symptoms Automatic Extraction

Retroperitoneal liposarcoma with leiomyosarcomatous differentiation.

[dedifferentiated liposarcoma]

We herein describe a 60-year-old Japanese man with a giant retroperitoneal liposarcoma undergoing leiomyosarcomatous differentiation. He was admitted to our hospital because of a 5-month history of dysphagia and abdominal distention. Abdominal computed tomography showed a giant tumor that occupied the entire retroperitoneal space. The majority of the mass was lipomatous and low density; both a heterogenous and solid mass were also present. A giant retroperitoneal liposarcoma was diagnosed, and tumor resection was performed. At surgery, the tumor was mostly isolated from the retroperitoneum and other organs. Histopathologically, the tumor comprised well-differentiated and dedifferentiated liposarcoma with heterologous differentiation of the leiomyosarcomatous components, which is a rare phenomenon in liposarcoma. The patient was alive 3 years after the first treatment, although he has had 3 local recurrences (approximately one recurrence yearly) and has been treated by repeated resection and radiotherapy.

Diseases presenting "dysphagia" symptom

  • alexander disease
  • cadasil
  • cushing syndrome
  • dedifferentiated liposarcoma
  • dystrophic epidermolysis bullosa
  • epidermolysis bullosa simplex
  • esophageal adenocarcinoma
  • esophageal carcinoma
  • esophageal squamous cell carcinoma
  • familial hypocalciuric hypercalcemia
  • inclusion body myositis
  • kindler syndrome
  • liposarcoma
  • locked-in syndrome
  • neuralgic amyotrophy
  • oligodontia
  • triple a syndrome
  • well-differentiated liposarcoma

This symptom has already been validated