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[A case of recurrent liposarcoma treated with bevacizumab chemotherapy resulting in prolonged disease-free survival and long-term overall survival].
[dedifferentiated liposarcoma]
Retroperitoneal
dedifferentiated
liposarcoma
is
associated
with
a
poor
prognosis
,
and
the
efficacy
of
chemotherapy
in
such
cases
is
controversial
.
We
report
a
case
of
long
-
term
survival
in
a
patient
with
dedifferentiated
liposarcoma
treated
with
bevacizumab
after
repeated
local
recurrences
.
A
65
-
year
-old
man
complained
of
abdominal
pain
.
Abdominal
computed
tomography
(
CT
)
showed
a
well-enhanced
retroperitoneal
tumor
.
The
tumor
was
resected
together
with
the
right
kidney
and
adrenal
gland
.
On
the
basis
of
histopathological
findings
,
the
tumor
was
diagnosed
as
a
dedifferentiated
liposarcoma
adenocarcinoma
.
Eleven
months
later
,
local
recurrence
was
diagnosed
and
the
tumor
was
resected
.
Thereafter
,
repeated
local
recurrences
were
diagnosed
,
and
repeated
tumor
resections
were
performed
.
Local
recurrence
and
distant
metastasis
in
the
axilla
and
scapula
soft
tissue
was
detected
5
.
9
years
after
the
initial
operation
.
Bevacizumab
therapy
was
initiated
,
and
the
tumor
markedly
reduced
in
size
.
Bevacizumab
treatment
has
been
continued
for
6
.
7
years
after
the
initial
operation
,
with
no
tumor
recurrence
or
metastasis
.
Diseases
Validation
Diseases presenting
"tumor resections"
symptom
dedifferentiated liposarcoma
liposarcoma
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