[A case of recurrent liposarcoma treated with bevacizumab chemotherapy resulting in prolonged disease-free survival and long-term overall survival].

[dedifferentiated liposarcoma]

Retroperitoneal dedifferentiated liposarcoma is associated with a poor prognosis , and the efficacy of chemotherapy in such cases is controversial . We report a case of long -term survival in a patient with dedifferentiated liposarcoma treated with bevacizumab after repeated local recurrences . A 65 -year -old man complained of abdominal pain . Abdominal computed tomography (CT ) showed a well-enhanced retroperitoneal tumor . The tumor was resected together with the right kidney and adrenal gland . On the basis of histopathological findings , the tumor was diagnosed as a dedifferentiated liposarcoma adenocarcinoma . Eleven months later , local recurrence was diagnosed and the tumor was resected . Thereafter , repeated local recurrences were diagnosed , and repeated tumor resections were performed . Local recurrence and distant metastasis in the axilla and scapula soft tissue was detected 5 .9 years after the initial operation . Bevacizumab therapy was initiated , and the tumor markedly reduced in size . Bevacizumab treatment has been continued for 6 .7 years after the initial operation , with no tumor recurrence or metastasis .