Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Cystinuria: mechanisms and management.
[cystinuria]
Cystinuria
is
a
relatively
uncommon
cause
of
pediatric
stone
disease
,
but
has
significant
morbidity
if
not
properly
controlled
because
of
its
significant
stone
recurrence
rate
.
Cystinuria
is
caused
by
the
inability
of
the
renal
tubules
to
reabsorb
filtered
cystine
,
which
is
poorly
soluble
at
a
typical
urine
pH
<
7
.
Although
many
advances
have
been
made
in
the
understanding
of
the
genetic
and
physiological
basis
of
cystinuria
,
the
cornerstones
of
treatment
still
involve
stone
prevention
with
dietary
measures
and
pharmacological
therapy
,
coupled
with
surgical
interventions
for
stone
removal
.
Pharmacological
treatments
can
carry
significant
side
effects
that
must
be
monitored
and
can
limit
therapy
as
well
as
impede
compliance
.
Most
patients
will
require
surgical
intervention
for
stone
removal
,
although
compliance
with
prevention
strategies
reduces
the
need
for
intervention
.
Diseases
Validation
Diseases presenting
"the inability of the renal tubules to reabsorb filtered cystine"
symptom
cystinuria
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom