Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Multicentric mast cell tumors in a horse.
[cutaneous mastocytosis]
A
6
-
year
-old
female
Rocky
Mountain
horse
was
presented
for
evaluation
of
draining
tracts
and
distal
limb
subcutaneous
edema
on
the
left
front
and
left
hind
limbs
that
had
been
present
for
2
weeks
.
Direct
smears
of
fluid
collected
by
fine-needle
aspiration
of
subcutaneous
fluid
from
both
limbs
were
highly
cellular
with
a
predominance
of
eosinophils
accompanied
by
numerous
,
moderately
atypical
,
variably
granulated
mast
cells
.
The
cytologic
diagnosis
was
mast
cell
tumor
(
MCT
)
with
prominent
eosinophilic
infiltration
with
a
differential
diagnosis
of
eosinophilic
granuloma
.
Histologic
evaluation
of
surgical
biopsies
of
lesions
from
both
limbs
was
performed
on
sections
stained
with
H
&
E
,
toluidine
blue
,
and
Luna
stains
.
The
histologic
diagnosis
was
MCT
,
and
staining
with
toluidine
blue
and
Luna
stains
confirmed
the
presence
of
mast
cells
and
eosinophils
,
respectively
.
In
addition
,
the
mast
cells
strongly
expressed
CD
117
.
This
is
the
first
reported
case
of
cutaneous
mast
cell
neoplasia
in
a
horse
in
which
primary
presenting
complaints
were
draining
tracts
and
distal
limb
subcutaneous
edema
involving
multiple
limbs
.
This
case
illustrates
the
utility
of
staining
for
CD
117
expression
in
combination
with
traditional
stains
,
such
as
toluidine
blue
and
Luna
,
in
differentiating
MCTs
from
other
eosinophilic
lesions
in
horses
.
Diseases
Validation
Diseases presenting
"edema"
symptom
acute rheumatic fever
adrenomyeloneuropathy
aniridia
cadasil
canavan disease
classical phenylketonuria
coats disease
congenital toxoplasmosis
cushing syndrome
cutaneous mastocytosis
erythropoietic protoporphyria
esophageal carcinoma
fabry disease
familial mediterranean fever
focal myositis
harlequin ichthyosis
homocystinuria without methylmalonic aciduria
inclusion body myositis
lamellar ichthyosis
liposarcoma
lymphangioleiomyomatosis
malignant atrophic papulosis
pleomorphic liposarcoma
systemic capillary leak syndrome
trochlear dysplasia
von hippel-lindau disease
waldenström macroglobulinemia
This symptom has already been validated