Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Cutaneous mastocytosis combined with eruptive melanocytic nevi and melanoma. Coincidence or a linkage in the pathogenesis?
[cutaneous mastocytosis]
Cellular
combinations
in
the
same
neoplasm
can
have
intriguing
physiopathological
implications
,
which
may
be
useful
to
better
understand
the
biology
of
the
diseases
.
Urticaria
pigmentosa
in
association
with
eruptive
melanocytic
nevi
was
observed
in
a
female
patient
.
Maculopapular
lesions
extended
at
the
base
of
different
melanocytic
nevi
and
the
histopathological
examination
revealed
the
presence
of
a
mast
cell
population
in
the
papillary
and
reticular
dermis
combined
with
overlying
melanocytic
nevi
.
The
re
-evaluation
of
a
melanoma
removed
three
years
before
revealed
the
presence
of
the
same
pathological
features
.
Immunohistochemical
assays
showed
a
strong
positivity
to
Giemsa
,
Toluidine
blue
and
CD-
117
in
the
mast
cells
,
while
a
S-
100
reaction
was
observed
in
the
melanocytic
population
.
We
discuss
possible
pathogenetic
linkage
between
cutaneous
mastocytosis
and
melanoma
.
Diseases
Validation
Diseases presenting
"neoplasm"
symptom
adrenal incidentaloma
alexander disease
aromatase deficiency
carcinoma of the gallbladder
cholangiocarcinoma
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dentin dysplasia
erdheim-chester disease
esophageal adenocarcinoma
esophageal carcinoma
familial hypocalciuric hypercalcemia
focal myositis
hodgkin lymphoma, classical
hydrocephalus with stenosis of the aqueduct of sylvius
junctional epidermolysis bullosa
kabuki syndrome
liposarcoma
lymphangioleiomyomatosis
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wolf-hirschhorn syndrome
This symptom has already been validated