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[Pharyngeal A-streptococcal infection encountered in the practical work of an internal medicine specialist].
[acute rheumatic fever]
The
problem
of
pharyngeal
infections
caused
by
beta
-
hemolytic
streptococci
of
group
A
(
BHSA
)
remains
a
challenge
for
both
health
providers
and
general
medicine
.
The
present
paper
was
designed
to
provide
the
data
suggesting
the
"
reappearance
"
of
a
highly
virulent
BHSA
infection
and
a
rise
in
the
frequency
of
its
complications
(
such
as
acute
rheumatic
fever
and
toxic
shock
syndrome
)
and
to
substantiate
the
necessity
of
rational
antibacterial
therapy
for
the
management
of
this
pathology
.
The
agents
of
choice
for
the
treatment
of
acute
forms
of
BHSA
(
tonsillitis
and
pharyngitis
)
include
penicillins
(
amoxicillin
,
benzathine-penicillin
,
phenoxymethyl
penicillin
)
and
cephalosporins
of
the
first
generation
(
cephadroxyl
)
as
well
as
macrolids
(
spiramycin
,
azithromycin
,
roxithromycin
,
midecamycin
,
josamycin
)
for
the
patients
who
do
not
tolerate
beta
-lactam
antibiotics
.
Inhibitor-protected
penicillins
(
amoxicillin
,
clavulanate
)
or
cephalosporins
of
the
second
generations
(
cefuroxime-axetil
)
should
be
prescribed
to
the
patients
presenting
with
chronic
recurring
BHSA
characterized
by
the
rather
high
probability
of
colonization
of
the
site
of
infection
by
beta
-lactamase
producing
microorganisms
.
Lincosamine-derived
antibiotics
,
such
as
lincomycin
and
clindamycin
,
are
reserved
for
the
patients
with
acute
and
chronic
BHSA
(
tonsillitis
and
pharyngitis
)
.
Diseases
Validation
Diseases presenting
"fever"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
alexander disease
allergic bronchopulmonary aspergillosis
canavan disease
carcinoma of the gallbladder
child syndrome
congenital toxoplasmosis
cushing syndrome
cystinuria
dracunculiasis
erdheim-chester disease
esophageal adenocarcinoma
esophageal carcinoma
familial mediterranean fever
focal myositis
hodgkin lymphoma, classical
lamellar ichthyosis
legionellosis
locked-in syndrome
malignant atrophic papulosis
neonatal adrenoleukodystrophy
neuralgic amyotrophy
oculocutaneous albinism
papillon-lefèvre syndrome
pyomyositis
pyruvate dehydrogenase deficiency
scrub typhus
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
typhoid
waldenström macroglobulinemia
wolf-hirschhorn syndrome
This symptom has already been validated
