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Aldosterone-secreting adrenal cortical carcinoma. A case report and review of the literature.
[cushing syndrome]
Adrenal
cortical
carcinomas
(
ACC
)
are
rare
,
typically
aggressive
malignant
neoplasms
with
a
reported
incidence
of
1
-
2
cases
per
1
million
population
and
account
for
0
.
05
-
0
.
2
%
of
all
malignancies
.
The
majority
of
these
tumors
are
functional
with
approximately
60
%
of
patients
experiencing
endocrine
symptomatology
typically
characterized
by
Cushing
's
syndrome
(
40
%
)
or
a
mixed
hormonal
picture
of
Cushing
syndrome
seen
in
association
with
virilization
.
Rarely
,
patients
present
with
a
pure
hormonal
syndrome
of
feminization
or
hyperaldosteronism
,
6
and
2
.
5
%
,
respectively
.
We
report
a
case
of
a
76
-
year
-old
woman
presenting
with
recently
diagnosed
hypertension
secondary
to
primary
hyperaldosteronism
.
The
patient
underwent
laparoscopic
converted
to
an
open
adrenalectomy
and
a
diagnosis
of
adrenocortical
carcinoma
(
aldosteronoma
clinical
)
was
rendered
.
This
case
and
review
of
the
literature
highlight
that
while
rare
,
aldosterone-secreting
adrenal
cortical
carcinomas
may
occur
.
In
this
case
report
,
we
discuss
the
clinical
presentation
,
pathologic
findings
,
and
review
the
literature
for
adrenal
cortical
carcinomas
and
aldosterone-secreting
adrenal
cortical
carcinomas
.
Diseases
Validation
Diseases presenting
"hypertension"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
aniridia
aromatase deficiency
cadasil
child syndrome
cohen syndrome
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cushing syndrome
cystinuria
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
fabry disease
familial hypocalciuric hypercalcemia
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
holt-oram syndrome
homocystinuria without methylmalonic aciduria
hydrocephalus with stenosis of the aqueduct of sylvius
inclusion body myositis
kallmann syndrome
kindler syndrome
lamellar ichthyosis
lymphangioleiomyomatosis
pendred syndrome
primary effusion lymphoma
scrub typhus
severe combined immunodeficiency
sneddon syndrome
typhoid
von hippel-lindau disease
well-differentiated liposarcoma
werner syndrome
x-linked adrenoleukodystrophy
zellweger syndrome
This symptom has already been validated