Aldosterone-secreting adrenal cortical carcinoma. A case report and review of the literature.

[cushing syndrome]

Adrenal cortical carcinomas (ACC ) are rare , typically aggressive malignant neoplasms with a reported incidence of 1 -2 cases per 1 million population and account for 0 .05 -0 .2 % of all malignancies . The majority of these tumors are functional with approximately 60 % of patients experiencing endocrine symptomatology typically characterized by Cushing 's syndrome (40 %) or a mixed hormonal picture of Cushing syndrome seen in association with virilization . Rarely , patients present with a pure hormonal syndrome of feminization or hyperaldosteronism , 6 and 2 .5 %, respectively . We report a case of a 76 -year -old woman presenting with recently diagnosed hypertension secondary to primary hyperaldosteronism . The patient underwent laparoscopic converted to an open adrenalectomy and a diagnosis of adrenocortical carcinoma (aldosteronoma clinical ) was rendered . This case and review of the literature highlight that while rare , aldosterone-secreting adrenal cortical carcinomas may occur . In this case report , we discuss the clinical presentation , pathologic findings , and review the literature for adrenal cortical carcinomas and aldosterone-secreting adrenal cortical carcinomas .