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Should the monitoring protocols for adrenal incidentalomas be changed?
[cushing syndrome]
The
prevalence
of
adrenal
incidentalomas
is
increasing
with
the
aging
of
the
population
and
the
use
of
high
resolution
imaging
technics
.
Current
protocols
propose
a
comprehensive
monitoring
of
their
functional
and
morphological
state
,
but
with
no
conclusive
clinical
evidence
that
endorses
it
.
Retrospective
study
of
96
patients
diagnosed
with
adrenal
incidentaloma
between
2008
and
2012
.
We
evaluated
clinical
,
functional
and
imaging
at
baseline
and
during
follow-up
.
Initially
,
9
cases
were
surgically
removed
:
4
due
to
hyperfunction
(
2
Cushing
syndromes
and
2
pheochromocytomas
)
and
5
due
to
size
larger
than
4
cm
.
During
follow-up
one
case
of
pheochromocytoma
was
diagnosed
and
another
grew
more
than
1
cm
,
needing
surgery
.
In
98
.
86
%
of
nonfunctional
and
benign
lesions
,
there
was
no
functional
and
/
or
morphological
changes
in
the
final
evaluation
.
The
results
of
our
study
challenge
the
validity
of
current
diagnostic-therapeutic
protocols
of
incidentalomas
,
which
should
be
reassessed
in
prospective
studies
taking
into
account
efficiency
characteristics
.
Diseases
Validation
Diseases presenting
"but with no conclusive clinical evidence that endorses it"
symptom
adrenal incidentaloma
cushing syndrome
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