Rare Diseases Symptoms Automatic Extraction

Ectopic Cushing and other paraneoplastic syndromes in thoracic neuroendocrine tumors.

[cushing syndrome]

Overproduction of corticotropin by the pituitary gland or extrapituitary tumors leads to hypercortisolism or Cushing syndrome. Diagnosis of suspected Cushing syndrome involves 3 major steps: confirmation of hypercortisolism, differentiation between corticotropin-independent and corticotropin-dependent causes of Cushing syndrome, and distinction between pituitary and ectopic corticotropin production. A definitive diagnosis of ectopic corticotropin secretion requires stringent criteria, including reversal of the clinical picture after resection of the tumor and/or demonstration of corticotropin immunohistochemical staining within the tumor tissue.

Diseases presenting "tumor tissue" symptom

  • cushing syndrome
  • esophageal carcinoma
  • esophageal squamous cell carcinoma
  • hodgkin lymphoma, classical
  • severe combined immunodeficiency
  • von hippel-lindau disease
  • well-differentiated liposarcoma
  • wiskott-aldrich syndrome

You can validate or delete this automatically detected symptom