Medical conditions with neuropsychiatric manifestations.

[cushing syndrome]

Medical disease sometimes affects patients through neuropsychiatric manifestations . When neuropsychiatric symptoms are predominant , identifying medical disease early in the illness course is imperative because many of these conditions are reversible with appropriate treatment . A high index of suspicion is required on the part of clinicians , particularly when patients also present with physical signs or unexplained symptoms that might suggest a broader , systemic process . The processes that most commonly cause neuropsychiatric symptoms include infectious , autoimmune , endocrinologic , metabolic , and neoplastic diseases . This article focuses on the most common of these conditions , and conditions for which early diagnosis and treatment are particularly important .