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Adrenocorticotropic hormone-producing thymic neuroendocrine carcinoma with oncocytic features: A case report and review of literature.
[cushing syndrome]
Thymic
neuroendocrine
carcinomas
are
the
most
common
mediastinal
neuroendocrine
tumor
.
These
malignancies
are
not
often
diagnosed
by
fine-needle
aspiration
(
FNA
)
,
as
they
are
more
commonly
diagnosed
by
biopsy
or
excision
.
We
describe
a
case
of
a
FNA
of
a
paratracheal
mass
from
a
38
-
year
-old
man
who
presented
with
Cushing
syndrome
.
A
low
-grade
neuroendocrine
carcinoma
with
oncocytic
features
was
diagnosed
,
which
was
later
confirmed
by
excision
of
the
thymus
,
anterior
mediastinal
and
paratracheal
soft
tissue
,
and
lymph
nodes
.
Oncocytic
features
in
these
tumors
are
a
rare
finding
and
bring
metastatic
medullary
thyroid
carcinomas
as
well
as
other
metastases
into
the
differential
diagnosis
.
The
prognosis
of
neuroendocrine
carcinomas
in
this
location
is
worse
than
neuroendocrine
carcinomas
in
other
areas
,
and
close
follow-up
is
recommended
.
Diagn
.
Cytopathol
.
2014
.
©
2014
Wiley
Periodicals
,
Inc
.