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Role of enhanced visibility in evaluating polyposis syndromes using a newly developed contrast image capsule endoscope.
[cowden syndrome]
A
flexible
spectral
imaging
color
enhancement
system
was
installed
in
new
capsule
software
for
video
capsule
endoscopy
.
Contrast
image
capsule
endoscopy
(
CICE
)
is
a
novel
technology
using
light-emitting
diodes
selected
for
the
main
absorption
range
of
hemoglobin
.
We
assessed
the
feasibility
and
diagnostic
effi
cacy
for
small
bowel
surveillance
in
patients
with
polyposis
syndromes
.
Six
patients
with
polyposis
syndromes
,
four
with
familial
adenomatous
polyposis
and
one
each
with
Cowden
syndrome
(
CS
)
and
Cronkhite-
Canada
syndrome
(
CCS
)
were
examined
using
CICE
.
We
conducted
three
evaluations
to
assess
the
effect
on
the
numbers
of
the
detected
polyps
;
compare
polyp
diagnostic
rates
between
adenoma
and
hamartoma
;
and
assess
polyp
visibility
.
The
numbers
of
detected
polyps
and
diagnostic
accuracy
did
not
differ
signifi
cantly
between
pre-contrast
and
contrast
images
.
However
,
50
%
of
the
adenomatous
polyps
displayed
enhanced
visibility
on
contrast
images
.
CICE
contrast
images
exhibited
clearly
demarcated
lesions
and
improved
the
visibility
of
minute
structures
of
adenomatous
polyps
.
Hamartomatous
polyp
micro-structures
in
patients
with
CS
and
CCS
were
more
clearly
visualized
on
contrast
than
pre-contrast
images
.
CICE
is
an
effective
tool
for
enhancing
the
visibility
of
polyps
in
patients
with
polyposis
syndrome
.
Diseases
Validation
Diseases presenting
"improved the visibility of minute structures of adenomatous polyps"
symptom
cowden syndrome
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