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[Question marks concerning serological tests in congenital toxoplasmosis - a case report].
[congenital toxoplasmosis]
Two
weeks
after
delivery
of
a
healthy
term
neonate
,
the
mother
developed
lymph
node
syndrome
,
which
corresponded
serologically
to
acute
toxoplasmosis
.
The
blood
of
the
newborn
showed
positive
IgM
,
IgG
and
IgA
antibody
titers
against
Toxoplasma
gondii
with
a
low
avidity
of
IgG
.
The
newborn
did
not
show
any
clinical
signs
or
organ
damage
connected
to
toxoplasmosis
either
at
the
beginning
or
during
the
follow-up
.
The
IgA
and
IgM
titers
exhibited
a
decrease
over
time
,
while
the
KFR
,
IgG
antibody
titers
and
avidity
had
an
increasing
trend
.
A
sharp
increase
of
KFR
,
IgE
and
IgA
antibody
titers
was
detected
during
the
sixth
month
of
life
,
probably
due
to
maturation
of
the
immune
system
in
the
setting
of
an
asymptomatic
infection
with
T
.
gondii
.
This
short
increase
was
followed
by
a
subsequent
decrease
in
titers
of
these
antibodies
until
they
reached
negative
levels
during
the
21
st
month
of
life
.
The
evaluation
of
serological
results
in
newborns
infected
with
T
.
gondii
is
always
difficult
and
should
be
performed
by
an
expert
physician
.
Children
at
risk
should
be
placed
under
a
long
-term
follow-up
to
avoid
potential
development
of
toxoplasma
chorioretinitis
.
