Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
[Toxoplasmosis mother-to-child screening: study of cases followed in the Pasteur Institute of Tunis (2007-2010)].
[congenital toxoplasmosis]
Toxoplasmosis
when
occurring
during
pregnancy
can
be
transmitted
to
the
fetus
and
lead
to
congenital
toxoplasmosis
(
CT
)
.
Therefore
,
pregnant
women
are
a
risk
group
,
for
which
it
is
necessary
to
determine
the
serologic
profile
.
The
objective
of
this
study
is
to
determine
the
serologic
profile
of
toxoplasmosis
in
pregnant
women
followed
at
the
Parasitology
Laboratory
of
the
Pasteur
Institute
in
Tunis
,
to
establish
the
prevalence
of
toxoplasmic
infections
during
pregnancy
and
the
incidence
of
the
CT
,
noting
the
difficulties
faced
in
the
interpretation
of
serological
results
.
This
is
a
retrospective
study
concerning
2833
toxoplasmic
serologies
practiced
on
2070
pregnant
women
,
followed
at
the
Parasitology-
Mycology
Laboratory
of
the
Pasteur
Institute
of
Tunis
,
between
2007
and
2010
.
Serological
diagnosis
of
toxoplasmosis
was
done
by
ELISA
(
Enzyme
Linked
Immunosorbent
Assay
)
for
the
detection
of
Immunoglobulin
(
Ig
)
G
and
M
and
the
study
of
toxoplasmosis
IgG
avidity
.
Prenatal
diagnosis
was
performed
for
58
women
by
amniotic
fluid
sampling
.
Toxoplasma
gondii
was
detected
by
Polymerase
Chain
Reaction
(
PCR
)
.
At
birth
,
the
diagnosis
of
congenital
toxoplasmosis
was
established
based
on
serology
.
The
toxoplasmic
serologies
carried
out
have
shown
that
45
.
6
%
of
the
pregnant
women
were
formerly
immunized
while
49
.
6
%
had
a
negative
serology
.
A
toxoplasmosis
primary
infection
acquired
during
pregnancy
was
detected
in
79
cases
(
3
.
8
%
)
.
Among
them
,
33
%
had
a
true
seroconversion
while
67
%
had
a
recent
toxoplasmosis
infection
in
view
of
the
positivity
of
IgG
and
IgM
on
the
first
sample
with
a
low
index
of
avidity
(
IA
)
.
For
21
parturients
whose
serology
showed
the
presence
of
IgG
,
IgM
and
an
intermediate
or
high
IA
.
Among
the
58
parturients
in
whom
prenatal
diagnosis
was
performed
,
PCR
was
positive
in
four
cases
.
After
birth
,
six
cases
of
congenital
toxoplasmosis
were
detected
by
serology
.
Diseases
Validation
Diseases presenting
"first sample with a low index"
symptom
congenital toxoplasmosis
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom