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Prevalence of congenital toxoplasmosis among a series of Turkish women.
[congenital toxoplasmosis]
Toxoplasma
gondii
infection
during
pregnancy
causes
congenital
malformations
.
Pregnant
women
should
be
screened
for
this
infection
since
it
is
preventable
and
treatable
.
To
study
the
sero
prevalence
of
Toxoplasma
gondii
infection
among
pregnant
women
living
in
lzmir
,
Turkey
.
A
blood
sample
was
obtained
from
4651
women
aged
between
15
and
45
years
,
during
their
first
trimester
of
pregnancy
.
IgM
and
IgG
antibodies
against
Toxoplasma
gondii
were
measured
using
an
ELISA
assay
.
Among
women
with
both
IgG
and
IgM
antibodies
positive
,
an
IgG
avidity
test
was
performed
,
using
a
VIDAS
kit
.
I
gG
antibodies
were
positive
in
1871
(
39
.
9
%
)
participants
.
Of
these
,
48
(
2
.
5
%
)
also
had
positive
IgM
antibodies
.
In
41
of
these
48
women
,
the
IgG
avidity
test
was
performed
and
only
one
woman
had
a
low
avidity
.
This
woman
was
treated
with
Spiramycin
.
Her
offspring
had
an
intrauterine
growth
retardation
and
oligohydramnios
.
A
chorioretinitis
was
diagnosed
in
the
offspring
of
other
woman
with
both
antibodies
positive
.
In
this
series
,
the
prevalence
of
congenital
toxoplasmosis
was
low
.
However
,
women
with
positive
antibodies
against
Toxoplasma
Gondii
should
be
further
studied
and
followed
during
their
pregnancy
.
Diseases
Validation
Diseases presenting
"congenital malformations"
symptom
aniridia
congenital diaphragmatic hernia
congenital toxoplasmosis
focal myositis
hirschsprung disease
homocystinuria without methylmalonic aciduria
hydrocephalus with stenosis of the aqueduct of sylvius
kabuki syndrome
monosomy 21
oligodontia
wolf-hirschhorn syndrome
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