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Prevalence of congenital toxoplasmosis among a series of Turkish women.
[congenital toxoplasmosis]
Toxoplasma
gondii
infection
during
pregnancy
causes
congenital
malformations
.
Pregnant
women
should
be
screened
for
this
infection
since
it
is
preventable
and
treatable
.
To
study
the
sero
prevalence
of
Toxoplasma
gondii
infection
among
pregnant
women
living
in
lzmir
,
Turkey
.
A
blood
sample
was
obtained
from
4651
women
aged
between
15
and
45
years
,
during
their
first
trimester
of
pregnancy
.
IgM
and
IgG
antibodies
against
Toxoplasma
gondii
were
measured
using
an
ELISA
assay
.
Among
women
with
both
IgG
and
IgM
antibodies
positive
,
an
IgG
avidity
test
was
performed
,
using
a
VIDAS
kit
.
I
gG
antibodies
were
positive
in
1871
(
39
.
9
%
)
participants
.
Of
these
,
48
(
2
.
5
%
)
also
had
positive
IgM
antibodies
.
In
41
of
these
48
women
,
the
IgG
avidity
test
was
performed
and
only
one
woman
had
a
low
avidity
.
This
woman
was
treated
with
Spiramycin
.
Her
offspring
had
an
intrauterine
growth
retardation
and
oligohydramnios
.
A
chorioretinitis
was
diagnosed
in
the
offspring
of
other
woman
with
both
antibodies
positive
.
In
this
series
,
the
prevalence
of
congenital
toxoplasmosis
was
low
.
However
,
women
with
positive
antibodies
against
Toxoplasma
Gondii
should
be
further
studied
and
followed
during
their
pregnancy
.