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A random Abstract
Our Project
Our Team
The Austrian Toxoplasmosis Register, 1992-2008.
[congenital toxoplasmosis]
We
aimed
to
determine
the
incidence
of
primary
gestational
infections
with
Toxoplasma
gondii
and
congenital
toxoplasmosis
in
Austria
,
a
country
with
a
nationwide
prenatal
serological
screening
program
since
1974
.
We
analyzed
retrospective
data
from
the
Austrian
Toxoplasmosis
Register
of
pregnant
women
with
Toxoplasma
infection
and
their
offspring
with
births
between
1992
and
2008
,
identified
by
the
prenatal
mandatory
screening
program
.
Treatment
was
administered
to
women
from
diagnosis
of
a
Toxoplasma
infection
until
delivery
.
Infected
infants
were
treated
up
to
1
year
of
life
routinely
.
Clinical
manifestations
in
infected
infants
were
monitored
at
least
for
1
year
and
documented
in
the
register
.
The
Austrian
Toxoplasmosis
Register
included
2147
pregnant
women
with
suspected
Toxoplasma
infection
.
Annually
,
8
.
5
per
10
000
women
acquired
Toxoplasma
infection
during
pregnancy
,
and
1
.
0
per
10
000
infants
had
congenital
toxoplasmosis
(
13
%
mean
transmission
rate
)
.
Our
data
showed
that
women
treated
according
to
the
Austrian
scheme
had
a
6
-
fold
decrease
in
the
maternofetal
transmission
rate
compared
to
women
without
treatment
.
Results
from
the
Austrian
Toxoplasmosis
Register
show
the
efficiency
of
the
prenatal
screening
program
.
Our
results
are
of
clinical
relevance
for
infants
,
healthcare
systems
,
and
policy
makers
to
consider
preventive
Toxoplasma
screening
as
a
potential
tool
to
reduce
the
incidence
of
congenital
toxoplasmosis
.
