Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Associated anomalies in congenital diaphragmatic hernia: perinatal characteristics and impact on postnatal survival.
[congenital diaphragmatic hernia]
Abstract
Objective
:
We
aimed
to
investigate
the
clinical
characteristics
and
postnatal
outcomes
of
fetuses
with
congenital
diaphragmatic
hernia
(
CDH
)
and
additional
anomalies
.
Materials
and
methods
:
We
reviewed
the
charts
of
fetuses
with
CDH
managed
between
2005
and
2013
.
Patients
were
divided
into
complex
and
isolated
groups
based
on
the
presence
of
additional
anomalies
.
We
analyzed
the
respective
polyhydramnios
,
liver
herniation
,
stomach
position
,
lung
to
thorax
transverse
area
ratio
(
LTR
)
,
and
prognoses
of
the
two
groups
.
The
survival
rates
of
both
groups
were
assessed
based
on
the
LTR
as
well
as
on
stomach
and
liver
positions
.
Results
:
CDH
was
diagnosed
in
65
fetuses
,
and
additional
anomalies
were
found
in
23
.
The
incidences
of
liver
herniation
,
polyhydramnios
,
and
death
were
significantly
higher
,
and
LTR
was
significantly
lower
,
in
the
complex
group
.
The
mortality
rate
of
fetuses
with
a
LTR
<
0
.
08
was
lower
than
that
of
fetuses
with
a
LTR
of
≥
0
.
08
in
the
complex
group
.
Further
,
the
survival
rate
of
fetuses
with
intrathoracic
liver
was
lower
than
those
without
liver
herniation
.
Conclusions
:
The
prognosis
of
complex
CDH
is
poor
.
This
may
result
from
both
the
associated
anomalies
and
the
severity
of
CDH
itself
.
Even
in
complex
CDHs
,
intrathoracic
liver
and
LTR
values
are
useful
in
estimating
postnatal
outcome
.
Diseases
Validation
Diseases presenting
"complex group"
symptom
congenital diaphragmatic hernia
heparin-induced thrombocytopenia
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom