Rare Diseases Symptoms Automatic Extraction

The lung to thorax transverse area ratio has a linear correlation with the observed to expected lung area to head circumference ratio in fetuses with congenital diaphragmatic hernias.

[congenital diaphragmatic hernia]

The purpose of this study was to clarify the relationship between the lung to thorax transverse area ratio (L/T ratio) and the observed to expected lung area to head circumference ratio (O/E LHR), based on the results of a nationwide Japanese survey conducted in 2011, and to evaluate the compatibility of these prognostic predictors of fetal CDH.Two hundred and forty-two prenatally diagnosed isolated CDH patients born between 2006 and 2010 were included in the present analysis. A regression analysis was conducted to investigate the relationship between the L/T ratio and the O/E LHR based on 191 simultaneous measurements of these parameters in 120 patients.The linear regression equation between the L/T ratio and the O/E LHR was: L/T ratio=0.0233+(0.00222×O/E LHR), (R=0.847, p<0.0001). According to this equation, 25% of the O/E LHR, the cut-off value used in the fetal intervention for CDH, was equivalent to an L/T ratio of 0.08, a commonly accepted cut-off value for identifying the most severe cases of fetal CDH.As there is a positive correlation between the L/T ratio and the O/E LHR, these two parameters proved to be used interchangeably according to the linear regression equation.

Diseases presenting "positive correlation" symptom

  • 22q11.2 deletion syndrome
  • acute rheumatic fever
  • adrenal incidentaloma
  • aromatase deficiency
  • congenital adrenal hyperplasia
  • congenital diaphragmatic hernia
  • cutaneous mastocytosis
  • dedifferentiated liposarcoma
  • familial mediterranean fever
  • hodgkin lymphoma, classical
  • inclusion body myositis
  • kallmann syndrome
  • legionellosis
  • oral submucous fibrosis
  • trochlear dysplasia
  • well-differentiated liposarcoma

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