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Neonatal gastric perforation: A single center experience.
[congenital diaphragmatic hernia]
To
determine
the
etiology
and
prognostic
factors
for
neonatal
gastric
perforation
(
NGP
)
,
a
rare
but
life-threatening
disease
.
Between
1980
and
2011
,
nine
patients
underwent
surgical
intervention
for
NGP
at
Seoul
National
University
Children
's
Hospital
.
The
characteristics
and
prognosis
of
the
patients
were
retrospectively
analyzed
.
Among
the
nine
patients
,
three
(
33
.
3
%
)
were
preterm
babies
and
five
(
55
.
5
%
)
had
associated
anomalies
,
which
included
diaphragmatic
eventration
(
n
=
2
)
,
congenital
diaphragmatic
hernia
,
esophageal
atresia
with
tracheoesophageal
fistula
,
and
antral
web
.
Three
(
33
.
3
%
)
patients
were
born
before
1990
and
three
(
33
.
3
%
)
had
a
birth
weight
<
2500
g
.
Pneumoperitoneum
was
found
on
preoperative
images
in
six
(
66
.
7
%
)
patients
,
and
incidentally
in
the
other
three
(
33
.
3
%
)
patients
.
Surgery
was
performed
within
24
h
after
the
onset
of
symptoms
in
seven
(
77
.
8
%
)
patients
.
The
overall
mortality
rate
was
22
.
2
%
(
2
/
9
)
.
The
time
between
symptoms
and
surgical
intervention
was
the
only
prognostic
factor
for
survival
,
whereas
premature
birth
and
birth
weight
were
not
.
Early
detection
and
advances
in
neonatal
intensive
care
may
improve
the
prognosis
of
NGP
.
Diseases
Validation
Diseases presenting
"early detection"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
adrenomyeloneuropathy
allergic bronchopulmonary aspergillosis
carcinoma of the gallbladder
child syndrome
cholangiocarcinoma
classical phenylketonuria
congenital diaphragmatic hernia
cowden syndrome
cystinuria
erythropoietic protoporphyria
esophageal adenocarcinoma
esophageal squamous cell carcinoma
fabry disease
homocystinuria without methylmalonic aciduria
inclusion body myositis
kallmann syndrome
krabbe disease
oral submucous fibrosis
papillon-lefèvre syndrome
phenylketonuria
pyomyositis
von hippel-lindau disease
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