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Correlation between lung to thorax transverse area ratio and observed/expected lung area to head circumference ratio in fetuses with left-sided diaphragmatic hernia.
[congenital diaphragmatic hernia]
Observed
/
expected
lung
area
to
head
circumference
ratio
(
o
/
e
LHR
)
and
lung
to
thorax
transverse
area
ratio
(
LTR
)
are
the
sonographic
indicators
of
postnatal
outcome
in
fetuses
with
congenital
diaphragmatic
hernia
(
CDH
)
,
and
they
are
not
influenced
by
gestational
age
.
We
aimed
to
evaluate
the
relationship
between
these
2
parameters
in
the
same
subjects
with
fetal
left-sided
CDH
.
Fetuses
with
left-sided
CDH
managed
between
2005
and
2012
were
included
.
Data
of
LTR
and
o
/
e
LHR
values
measured
on
the
same
day
prior
to
33
weeks
'
gestation
in
target
fetuses
were
retrospectively
collected
.
The
correlation
between
the
2
parameters
was
estimated
using
the
Spearman
's
rank-correlation
coefficient
,
and
linear
regression
analysis
was
used
to
assess
the
relationship
between
them
.
Data
on
61
measurements
from
36
CDH
fetuses
were
analyzed
to
obtain
a
Spearman
's
rank-correlation
coefficient
of
0
.
74
with
the
following
linear
equation
:
LTR
=
0
.
002
×
(
o
/
e
LHR
)
+
0
.
005
.
The
determination
coefficient
of
this
linear
equation
was
sufficiently
high
at
0
.
712
,
and
the
prediction
accuracy
obtained
with
this
regression
formula
was
considered
satisfactory
.
A
good
linear
correlation
between
the
LTR
and
the
o
/
e
LHR
was
obtained
,
suggesting
that
we
can
translate
the
predictive
parameters
for
each
other
.
This
information
is
expected
to
be
useful
to
improve
our
understanding
of
different
investigations
focusing
on
LTR
or
o
/
e
LHR
as
a
predictor
of
postnatal
outcome
in
CDH
.
