Acne as a chronic systemic disease.

[congenital adrenal hyperplasia]

Acne is the most common skin disorder . In the majority of cases , acne is a disease that changes its skin distribution and severity over time ; moreover , it can be a physically (scar development ) and psychologically damaging condition that lasts for years . According to its clinical characteristics , it can be defined as a chronic disease according to the World Health Organization criteria . Acne is also a cardinal component of many systemic diseases or syndromes , such as congenital adrenal hyperplasia , seborrhea -acne -hirsutism -androgenetic alopecia syndrome , polycystic ovarian syndrome , hyperandrogenism-insulin resistance -acanthosis nigricans syndrome , Apert syndrome , synovitis-acne -pustulosis-hyperostosis -osteitis syndrome , and pyogenic arthritis -pyoderma gangrenosum -acne syndrome . Recent studies on the Ache hunter gatherers of Paraguay detected the lack of acne in association with markedly lower rates of obesity , diabetes mellitus , hyperlipidemia , and cardiovascular diseases , a finding that indicates either a nutritional or a genetic background of this impressive concomitance .

Diseases
Validation

Diseases presenting "diabetes mellitus" symptom

acute rheumatic fever

adrenal incidentaloma

adrenomyeloneuropathy

allergic bronchopulmonary aspergillosis

alpha-thalassemia

child syndrome

cholangiocarcinoma

cohen syndrome

congenital adrenal hyperplasia

congenital toxoplasmosis

cowden syndrome

cushing syndrome

cystinuria

esophageal adenocarcinoma

esophageal carcinoma

esophageal squamous cell carcinoma

fabry disease

familial hypocalciuric hypercalcemia

malignant atrophic papulosis

neuralgic amyotrophy

pyomyositis

sneddon syndrome

typhoid

werner syndrome

wolf-hirschhorn syndrome

This symptom has already been validated