Rare Diseases Symptoms Automatic Extraction
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A random Abstract
Our Project
Our Team
Behavioural outcome in children with congenital adrenal hyperplasia: experience of a single centre.
[congenital adrenal hyperplasia]
The
aim
of
this
study
was
to
determine
the
behavioral
outcome
in
children
with
CAH
and
to
identify
the
risk
factors
that
may
influence
it
.
Participants
(
aged
6
-
18
years
)
included
29
girls
and
20
boys
with
CAH
and
unaffected
siblings
(
25
girls
and
17
boys
)
.
Psychological
adjustment
was
assessed
with
parent
reports
on
the
Child
Behavior
Checklist
(
CBCL
)
.
Information
about
disease
characteristics
was
obtained
from
medical
records
.
Our
study
reveals
that
there
was
higher
incidence
of
parent-reported
problem
of
anxious
/
depressed
and
withdrawn
/
depressed
behaviours
,
somatic
complaints
,
social
,
thought
,
and
attention
problems
,
and
rule-breaking
,
aggressive
,
internalizing
,
and
externalizing
behaviour
among
children
with
CAH
compared
to
controls
.
The
prevalence
of
internalizing
behaviour
problems
was
higher
in
CAH
boys
compared
with
that
of
controls
.
Psychosocial
adjustment
of
girls
with
CAH
was
found
to
be
similar
to
unaffected
female
controls
and
was
within
the
normal
population
range
.
Family
income
may
be
associated
with
behavioral
outcome
.
Glucocorticoid
dose
may
reflect
disease
severity
which
may
be
associated
with
behavioral
outcome
.
We
conclude
that
internalizing
behavioral
problem
was
prevalent
among
boys
with
CAH
reflecting
maladaptive
adjustment
in
coping
with
chronic
illness
.
This
highlighted
the
importance
of
psychological
and
social
support
for
the
patients
and
their
families
.
