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Testicular Adrenal Rest Tumors in Congenital Adrenal Hyperplasia-A Case Report and Literature Overview.
[congenital adrenal hyperplasia]
Objective
:
In
this
paper
,
the
etiology
,
differential
diagnosis
and
therapy
of
testicular
adrenal
rest
tumors
was
presented
based
on
a
patient
presentation
and
an
overview
of
the
most
recent
literature
concerning
this
subject
.
Methods
:
Retrospective
analysis
of
the
clinical
and
biochemical
data
of
an
18
-
year
old
male
patient
diagnosed
at
the
age
of
2
weeks
with
the
classic
salt-wasting
form
of
congenital
adrenal
hyperplasia
that
has
been
monitored
in
the
Pediatric
and
Adolescent
Out-
Patient
Department
since
the
age
of
4
years
.
Results
:
The
results
of
adrenal
hormone
concentrations
(
17
-
OHP
,
17
KS
,
pregnans
)
had
been
unsatisfactory
,
especially
in
last
5
years
.
Scrotal
US
detected
TARTs
bilaterally
.
After
increasing
the
dose
of
hydrocortisone
and
introducing
dexamethasone
considerable
regression
of
the
tumors
was
noted
.
Conclusion
:
Lack
of
complete
regression
of
the
lesions
is
caused
by
fibrosis
and
is
probably
due
to
decreased
sensitivity
of
ACTH
and
angiotensin
II
receptors
in
this
tissue
.
