Behavioural characteristics and autistic features in individuals with Cohen Syndrome.

[cohen syndrome]

Diagnostic criteria for Cohen Syndrome are based largely on physical characteristics , and systematic information about behaviour and social functioning is limited . Typically , individuals with this condition are described as being very sociable and as showing low rates of pathology . However , recent studies have indicated that behavioural difficulties may occur more frequently than previously suggested and that autistic features may be relatively common . The present investigation of 45 individuals with Cohen Syndrome (age 4 -48 years ) found that , although 57 % of the sample were reported as showing some behavioural disturbance , problems related mainly to anxiety and social interactions ; marked anti-social behaviours were rare . Twenty -two individuals met criteria for autism on standardised diagnostic assessments , although the "autistic profile " was somewhat atypical . The implications of these findings for our understanding of Cohen Syndrome are discussed .

Diseases
Validation

Diseases presenting "anxiety" symptom

22q11.2 deletion syndrome

achondroplasia

adrenal incidentaloma

adrenomyeloneuropathy

cadasil

child syndrome

classical phenylketonuria

cohen syndrome

congenital adrenal hyperplasia

congenital toxoplasmosis

cutaneous mastocytosis

fabry disease

familial hypocalciuric hypercalcemia

familial mediterranean fever

gm1 gangliosidosis

hereditary cerebral hemorrhage with amyloidosis

junctional epidermolysis bullosa

locked-in syndrome

monosomy 21

oligodontia

oral submucous fibrosis

phenylketonuria

von hippel-lindau disease

x-linked adrenoleukodystrophy

This symptom has already been validated